HIV-1 regulatory Tat protein plays an essential role in viral replication and infectivity. In addition, during acute infection, Tat is released extracellularly by infected cells and is taken up by neighbouring cells where it transactivates viral replication and increases virus infectivity. The Tat cys22 protein of HIV-1 is a molecule of 86 aminoacids mutated in the trans activation domain.
Recombinant TAT Cys22
Description
HIV-1 regulatory tat protein plays an essential role in viral replication and infectivity. In addition, during acute infection tat is released in the extracellular environment by infected cells and is taken up by neighbouring cells where it transactivates viral replication and increases virus infectivity. The tat cys22 protein of HIV-1 is a molecule of 86 aminoacids mutated in the trans activation domain.
Additional information
| Size | 50 µg |
|---|---|
| Application | Clinical diagnostics| Life Sciences |
| Product type | Reagents for research |
| Reagent type | Recombinant protein |
| Category | HIV |
| Subcategory | TAT Protein (Transactivating regulatory protein) |
Technical information
| Accession number | GenBank CAL40981.1 |
|---|---|
| Organism | Synthetic construct |
| Size | 50 µg |
| Potency | Not biologically Active protein |
| Expression system | E.coli |
| Tag | No tags |
| Purity | >90% |
| Form | Lyophilized with 0.1% glycerol. |
| Tested application | WB, SDS-PAGE, Endotoxins, Up-take, Rescue assay |
| Solubility | The protein should be reconstituted in apirogenic sterile water or 1X PBS |
| Shipping/storage conditions | Shipped at RT. The lyophilized protein is stable for 24 months if stored at -20°C. The reconstituted solution has to be used immediately. Avoid freeze-thaw cycles. |
| Usage | For Laboratory Research Use Only |
