Recombinant p24 is a 24 kDa, full length protein produced in E. coli.
HIV-1 Gag protein is a polyprotein which, during viral maturation, is cleaved to release matrix p17, core p24 and nucleopcapsid proteins. Capsid protein p24 forms the conical core that encapsulates the genomic RNA-nucleocapsid complex in the virion. The core is constituted by capsid protein hexamer subunits and is disassembled soon after virion entry. The p24 antigen contains epitopes that prime helper CD4 T-cells, which have been demonstrated to be protective and it can elicit lymphocyte proliferation.
|Application||Clinical diagnostics| Life Sciences|
|Product type||Reagents for research|
|Reagent type||Recombinant protein|
|Subcategory||Capsid protein p24 HIV-1 Gag p24|
|Accession number||UniProt Q9WMV8|
|Organism||Human immunodeficiency virus 1|
|Form||Lyophilized with 1% glycerol.|
|Tested application||SDS-PAGE, WB|
|Solubility||The protein should be reconstituted in apirogenic sterile water or 1X PBS|
|Shipping/storage conditions||Shipped at RT The lyophilized protein is stable for 24 months if stored at -20°C. The reconstituted solution has to be used immediately. Avoid freeze-thaw cycles.|
|Usage||For Laboratory Research Use Only|