p24 protein is the major core protein of HIV virus particle and has been suggested as a specific target for antiviral strategies. The anti p24 polyclonal antibody would be useful for detect p24 protein as a useful tool on HIV-1 reserch. Polyclonal anti p24 antibody is designed for the detection of p24 core antigen in human serum or plasma from infected individuals as well as in cell culture supernatant.
Rabbit Anti HIV-1 p24
Description
The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins which are required for virus particle assembly. p24 protein is detectable starting from the early stage of AIDS virus infection, for this reason it is an interesting marker for disease progression in infected patients. HIV-1 p24 is a major viral core structural protein. Its measurement is commonly used as an indicator of HIV-1 infection and viral load.
Additional information
| Size | 200 µL |
|---|---|
| Application | Clinical diagnostics| Life Sciences |
| Product type | Reagents for research |
| Reagent type | Antibody |
| Category | HIV |
| Subcategory | Polyclonal anti p24 antibody |
| Antibody type | Primary antibody |
| Immunogen | Recombinant purified p24 protein (HIV-1 ) expressed in E.coli |
Technical information
| Accession number | GenBank AAP33775.1 |
|---|---|
| Size | 200 µL |
| Purity | Purified by Protein A affinity Chromatography |
| Form | Liquid. Supplied in 100mM sodium citrate, 50mM Tris and 0.05% v/v glycerol. Neutral pH. |
| Shipping/storage conditions | Shipped at 2-8°C. When stored at +4°C the antibody is stable for 18 months. For extended storage up to 24 months, the solution may be frozen at -20°C in working aliquots. Avoid repested freezing and thawing cycles. |
| Usage | For Laboratory Research Use Only |
| Source | Rabbit |
| Specificity | HIV-1 p24 from human serum or plasma and in cell culture supernatants |
| React with | P24 from HIV-1 |
| Recommended dilutions | Recommended starting dilutions can vary lot-to-lot. Consult the suggested starting dilutions on the top of the page for lot specific values. |
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References
| IFI16 Expression Is Related to Selected Transcription Factors during B-Cell Differentiation | PUBMED ID: 26185770 |
