Rabbit Anti HIV-1 p24

p24 protein is the major core protein of HIV virus particle and has been suggested as a specific target for antiviral strategies. The anti p24 polyclonal antibody would be useful for detect p24 protein as a useful tool on HIV-1 reserch. Polyclonal anti p24 antibody is designed for the detection of p24 core antigen in human serum or plasma from infected individuals as well as in cell culture supernatant.

SKU: ANT0033 Categories: , , ,
Product type: Reagents for research
Reagent type: Antibody
Size: 200 µL

Description

The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins which are required for virus particle assembly. p24 protein is detectable starting from the early stage of AIDS virus infection, for this reason it is an interesting marker for disease progression in infected patients. HIV-1 p24 is a major viral core structural protein. Its measurement is commonly used as an indicator of HIV-1 infection and viral load.

Additional information

Size 200 µL
Application Clinical diagnostics| Life Sciences
Product type Reagents for research
Reagent type Antibody
Category HIV
Subcategory Polyclonal anti p24 antibody
Antibody type Primary antibody
Immunogen Recombinant purified p24 protein (HIV-1 ) expressed in E.coli

Technical information

Accession number GenBank AAP33775.1
Size 200 µL
Purity Purified by Protein A affinity Chromatography
Form Liquid. Supplied in 100mM sodium citrate, 50mM Tris and 0.05% v/v glycerol. Neutral pH.
Shipping/storage conditions Shipped at 2-8°C. When stored at +4°C the antibody is stable for 18 months. For extended storage up to 24 months, the solution may be frozen at -20°C in working aliquots. Avoid repested freezing and thawing cycles.
Usage For Laboratory Research Use Only
Source Rabbit
Specificity HIV-1 p24 from human serum or plasma and in cell culture supernatants
React with P24 from HIV-1
Recommended dilutions Recommended starting dilutions can vary lot-to-lot. Consult the suggested starting dilutions on the top of the page for lot specific values.

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References

IFI16 Expression Is Related to Selected Transcription Factors during B-Cell Differentiation PUBMED ID: 26185770

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