Recombinant Listeriolysin-O (LLO)

Recombinant Listeriolysin O (LLO) is a protein produced in E. coli. LLO is a single polypeptide protein composed of 529 residues lacking the secretion signal peptide (1-25 aa).

SKU: REP0006 Categories: , , , ,
Product type: Reagents for research
Reagent type: Recombinant protein
Size: 50 µg

Description

The secreted pore-forming protein listeriolysin O (LLO) is an essential virulence determinant of the facultative intracellular bacterium Listeria monocytogenes that allows the pathogen to escape from the phagocytic vacuole and reach the host cytosol. LLO is a single polypeptide protein encoded by the hlyA gene and composed of 529 residues

Additional information

Size 50 µg
Application Clinical diagnostics| Veterinary diagnostics| Life Sciences
Product type Reagents for research
Reagent type Recombinant protein
Category Listeria monocytogenes
Subcategory Listeriolysin-O

Technical information

Accession number GenBank AF253320.1 lacking the secretion signal peptide (1-25aa)
Organism L. monocytogenes
Size 50 µg
Potency Biologically active protein
Expression system E.coli
Tag No tags
Purity >90%
Form Liquid, 50mM NaH2PO4 , 0.5M NaCl, 2.7mM KCl, 1mM EDTA, 1mM DTT, 5%(v/v) glycerol.
Tested application WB, SDS-PAGE, Endotoxins, Up-take, Rescue assay
Shipping/storage conditions Shipped in dry ice . The protein is stable for 12 months if stored at -80°C. Avoid freeze-thaw cycles.
Usage For Laboratory Research Use Only

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References

A Novel Role of Listeria monocytogenes Membrane Vesicles in Inhibition of Autophagy and Cell Death PUBMED ID: 28516064

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