Recombinant Listeriolysin O (LLO) is a protein produced in E. coli. LLO is a single polypeptide protein composed of 529 residues lacking the secretion signal peptide (1-25 aa).
Recombinant Listeriolysin-O (LLO)
Description
The secreted pore-forming protein listeriolysin O (LLO) is an essential virulence determinant of the facultative intracellular bacterium Listeria monocytogenes that allows the pathogen to escape from the phagocytic vacuole and reach the host cytosol. LLO is a single polypeptide protein encoded by the hlyA gene and composed of 529 residues
Additional information
| Size | 100 µg |
|---|---|
| Application | Clinical diagnostics| Veterinary diagnostics| Life Sciences |
| Product type | Reagents for research |
| Reagent type | Recombinant protein |
| Category | Listeria monocytogenes |
| Subcategory | Listeriolysin-O |
Technical information
| Accession number | GenBank AF253320.1 lacking the secretion signal peptide (1-25aa) |
|---|---|
| Organism | L. monocytogenes |
| Size | 100 µg |
| Potency | Biologically active protein |
| Expression system | E.coli |
| Tag | No tags |
| Purity | >90% |
| Form | Liquid, 50mM NaH2PO4 , 0.5M NaCl, 2.7mM KCl, 1mM EDTA, 1mM DTT, 5%(v/v) glycerol. |
| Tested application | WB, SDS-PAGE, Endotoxins, Up-take, Rescue assay |
| Shipping/storage conditions | Shipped in dry ice . The protein is stable for 12 months if stored at -80°C. Avoid freeze-thaw cycles. |
| Usage | For Laboratory Research Use Only |
Download
References
| A Novel Role of Listeria monocytogenes Membrane Vesicles in Inhibition of Autophagy and Cell Death | PUBMED ID: 28516064 |
