Streptococcus mutans is a Gram-positive bacterium that lives in the mouth. The bacterium metabolizes different kinds of carbohydrates, creating an acidic environment in the mouth as a result of this process. This acidic environment in the mouth is what causes the tooth decay. S. mutans is considered to be the most cariogenic of all of the oral Streptococci. The antibody against S.Mutans is an aid in the oral pathogens reaserch and in the diagnostic test development.
Rabbit anti Streptococcus mutans FITC
Description
One of the important virulence properties of these organisms is their ability to form biofilms known as dental plaque on tooth surfaces. Biofilms are sessile bacterial communities adherent to a surface, and their formation occurs in response to a variety of environmental causes. S. mutans undergoes a developmental program in response to environmental signals that leads to the expression of new phenotypes that distinguish these sessile cells from planktonic cells. Microbiological studies have been conducted in particular in patients undergoing treatment for cancer. Radiotherapy-caused hyposalivation may affect the oral microbiota. Variations in quantity, complexity, and quality of the oral microbiota also occur during chemotherapy, leading to a major imbalance of the ecosystem. As the bacteria develop in the mouth, they cause tooth destruction, impaired speech, difficulty chewing, multiple infections, psychological problems such as low self-esteem, poor social interactions, concentration problems, etc. Though not fatal, tooth decay is one of the most common infectious diseases in humans. The bacteria are most concentrated in the crevices, pits, and fissures that are a normal part of the teeth and surrounding structures. Adults may have a high concentration of S. mutans in their mouths. In contrast, infants and children have a smaller concentration, but they are more vulnerable to the bacteria.
Additional information
| Size | 200 µL |
|---|---|
| Application | Clinical diagnostics| Life Sciences |
| Product type | Reagents for research |
| Reagent type | Antibody |
| Category | Oral pathogens |
| Subcategory | Polyclonal anti S.Mutans |
| Antibody type | Secondary antibody |
| Immunogen | S. Mutans ATCC 25175 inactivated cells |
Technical information
| Size | 200 µL |
|---|---|
| Purity | Purified by affinity Chromatography |
| Form | Liquid. Supplied in PBS. Neutral pH. |
| Shipping/storage conditions | Shipped at 2-8°C. When stored at +4°C the antibody is stable for 18 months. For extended storage up to 24 months, the solution may be frozen at -20°C in working aliquots. Avoid repested freezing and thawing cycles. |
| Usage | For Laboratory Research Use Only |
| Source | Rabbit |
| Specificity | Antibody binds S. Mutans. Low reactivity against S.Oralis, P.Gingivalis, F.nucleatum |
| React with | Antibody binds Streptococcus mutans |
| Recommended dilutions | Recommended starting dilutions can vary lot-to-lot. Consult the suggested starting dilutions on the top of the page for lot specific values. |
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References
| A dual-species microbial model for studying the dynamics between oral streptococci and periodontal pathogens during biofilm development on titanium surfaces by flow cytometry | PUBMED ID: 27032997 |
