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ZMPSTE24 Gene Amplification Kit for direct sequencing

The ZMPSTE24 gene amplification kit for direct sequencing is intended for the simultaneous amplification of all exons included in human ZMPSTE24 gene through ready-to-use mixes, for a rapid and direct sequencing of ZMPSTE24 coding region using only M13 primers.

SKU: MBK0025 Categories: , ,
Application: Clinical Diagnostics
Product type: Diagnostic kit
Reagent type: PCR
Size: 108 tests

Description

ZMPSTE24 is a metalloproteinase involved in the maturation of the Lamin A protein. Lamin A is an essential component of the nuclear membrane, providing structural function and transcriptional regulation in the cell nucleus. Different human progeroid syndromes are caused by mutations in ZMPSTE24 or LMNA genes which undergo under the term laminopathies. The ZMPSTE24 gene amplification kit for direct sequencing is intended for the simultaneous amplification of all exons included in human ZMPSTE24 gene. After PCR, all amplicons can be easily sequenced with M13 universal primers.

Additional information

Size 108 tests
Application Clinical diagnostics
Product type Diagnostic kit
Reagent type PCR
Category Aging-Laminopathies

Technical information

Size 108 tests
Technology End-point PCR
Specimen Human DNA
Testing time 2 hours
Target gene ZMPSTE24 gene exons

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References

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