The recombinant Thymidine Phosphorylase is a 49 kDa protein with N-terminal His tag expressed in E.coli.
Recombinant Escherichia coli Thymidine Phosphorylase
Thymidine phosphorylase (TYMP) is an enzyme involved in pyrimidine metabolism; the enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Defects in TYMP are the cause of mitochondrial DNA depletion syndrome type 1 (MTDPS1) also known as myoneurogastrointestinal encephalomyopathy (MNGIE), a multisystem disease associated with mitochondrial dysfunction.
|Application||Clinical diagnostics| Life Sciences|
|Product type||Reagents for research|
|Reagent type||Recombinant protein|
|Accession number||GenBank WP_000477811.1|
|Organism||thymidine phosphorylase [Enterobacteriaceae].|
|Form||Liquid, 20mM K2HPO4/NaH2PO4 pH 7.5; 140mM NaCl; 3mM MSH; 10% glycerol.|
|Shipping/storage conditions||Shipped at -20°C. The protein is stable for 12 months if stored at -80°C. Avoid repeated freeze/thaw cycles.|
|Usage||For Laboratory Research Use Only|