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Recombinant Escherichia coli Thymidine Phosphorylase

The recombinant Thymidine Phosphorylase is a 49 kDa protein with N-terminal His tag expressed in E.coli.

SKU: REP0064 Categories: , , ,
Product type: Reagents for research
Reagent type: Recombinant protein
Size: 5000 U

Description

Thymidine phosphorylase (TYMP) is an enzyme involved in pyrimidine metabolism; the enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Defects in TYMP are the cause of mitochondrial DNA depletion syndrome type 1 (MTDPS1) also known as myoneurogastrointestinal encephalomyopathy (MNGIE), a multisystem disease associated with mitochondrial dysfunction.

Additional information

Size 5000 U
Application Clinical diagnostics| Life Sciences
Product type Reagents for research
Reagent type Recombinant protein
Category Tumor markers

Technical information

Accession number GenBank WP_000477811.1
Organism thymidine phosphorylase [Enterobacteriaceae].
Size 5000 U
Potency Enzymatic activity
Expression system E.coli
Tag HIS tagged
Purity >95%
Form Liquid, 20mM K2HPO4/NaH2PO4 pH 7.5; 140mM NaCl; 3mM MSH; 10% glycerol.
Tested application SDS-PAGE/WB/
Shipping/storage conditions Shipped at -20°C. The protein is stable for 12 months if stored at -80°C. Avoid repeated freeze/thaw cycles.
Usage For Laboratory Research Use Only

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